A former American assistant military attache now living in Phuket, an island in the Andaman Sea in southern Thailand, joins force with a female Thai marine scientist to foil an assassination attempt on the visiting US president by an international drug trafficking cartel. The assassins discover the deadly venom of a geography cone snail which has a bizarre and fatal result called the King Kong effect which is unstoppable and there is no antivenin. The former attache and the marine scientist must survive through a series of adventures in a race against time and ruthless assassins to save the US president from the King Kong effect.